Today marks the start of Dementia Awareness Week 2013, a national campaign to raise the profile of the many different forms of dementia, from Alzheimer’s to Parkinson’s disease.
More than 300,000 Aussies are estimated to be living with dementia – a figure which is set to almost triple by 2050. So how can we help lower our risk in the future?
Experts from Alzheimer’s Australia say we need to understand the connection between our physical health and our brain health. As we get older, it’s important that we take care of both our bodies and our brains.
Serious chronic illnesses like heart disease, stroke and diabetes, plus risk factors including depression, obesity and sleep are all associated with cognitive decline. If left unchecked, these conditions can increase our risk of developing a range of debilitating diseases including dementia.
So while there may not be a cure, we can help reduce our risk of dementia by maximising our brain health and managing our blood sugar, cholesterol levels, blood pressure and body weight.
Learn more about our work in the early detection of Alzheimer’s disease – the most common form of dementia.
Dementia Awareness Week runs from 16 to 22 September. Head to Alzheimer’s Australia for more information.
Media: Andreas Kahl, Andreas.Kahl@csiro.au T: 08 8303 8888 M: 0407 751 330
It’s not often we get to dress up and hit the red carpet, so when it happens we like to brag about it.
Last night we took to the Sydney Opera House to celebrate the 19th annual Deadlys. These prestigious awards recognise the achievements of Aboriginal and Torres Strait Islander people across a range of fields in our community.
While it was a nice excuse to rub shoulders with superstar Jessica Mauboy and photobomb RedFoo from LMFAO, that’s not why we were there.
This year a new award was added to the Deadlys – the inaugural Deadly Award for Indigenous Scientist or Science Project of the Year – and we were chuffed to be sponsoring it. The award recognises the significant contributions made by Indigenous people working in science roles or science projects.
Nominations were received from members of the public and five finalists were selected by a panel of deadly experts.
And the winner is: Gerry Turpin.
Gerry is an ethnobotanist at the Australian Tropical Herbarium in Cairns. He is working with our researchers and a range of other organisations to develop an Indigenous driven tropical ethnobotanical centre, known as TIEC.
The TIEC is the first of its kind in Australia and will help Traditional Owners in tropical Queensland apply their Indigenous environmental knowledge for cultural use on-country.
A big congratulations to Gerry and all of this year’s winners.
By Carrie Bengston
You might not realise, but we use maths in nearly all of our daily activities. Every time we check the weather, use the internet or travel anywhere, maths plays a part. On a larger scale, maths can even be used to protect our flora and fauna from invasive pests. Our Biosecurity Flagship Director Dr Gary Fitt explains.
Q: You’ve said we don’t want Australia to become a zoo. What do you mean?
A: Zoos have collections of animals from all around the world. While they’re fun to visit, we don’t want Australia to become one. Australia already has its own magnificent native flora and fauna. We’re an island continent and our wildlife really is unique in the world.
Take the Gouldian Finch for example. I’ve just spent a week in the Kimberley region of WA observing and counting these spectacularly colourful little birds. These endangered species are found nowhere else in the world but northern Australia. It would be tragic if they were lost from nature because of the introduction of a pest or disease.
With the world so connected by air and sea, the risks are real that Australia could become a zoo of introduced species alongside a reduced set of native ones.
It’s not just animals either – our plants are unique too. Botany Bay, where Captain James Cook landed, is named after the science of plants because so many unusual plant specimens were collected there by Joseph Banks. Unfortunately, our bushland today can become a new home for invasive plants, like the garden escapees lantana and privet.
We don’t want invasive animals, plants or even micro-organisms from other parts of the world coming in and getting a foothold. Australia’s ecosystems would change forever, affecting health and agriculture. We need to protect our own biodiversity as much as we can. Our biosecurity research is key to that. It’s in our interests and future generations’ interests to get that right.
Q: You’ve enlisted mathematicians and statisticians to work on this research. What do they bring to the field of biosecurity?
Biosecurity is in a sense a game of probabilities. In this game the mathematical sciences are critical in two ways.
The first is to do with risk. Maths can help us determine the chances of a particular pest arriving and surviving in Australian environments, often in the face of uncertainties. By better understanding the risks and pathways, we can optimise investments in the right kind of surveillance systems. For instance, some of our projects quantify the riskiest pathways of entry in Australia, while others look at where to focus surveillance in ports.
The second is to do with response. Once a pest has arrived here, how do we get rid of it or limit its spread? We need to choose strategies that have the greatest chance of success. Once implemented, we need to know whether those methods are working.
By making decisions based on statistical inference from the available data, rather than gut feel or vested interests, we can help policy makers and operational Biosecurity players better target funds for response. Maths is also important for modelling the life cycle stages of invasive species which might be most vulnerable to biological control.
Q: It’s Canberra’s centenary year. How has research in Canberra contributed to our understanding of bioinvasion and biosecurity?
A: Canberra is and has been home to some of Australia’s most famous research into invasive pests.
Canberra was where the ANU’s Frank Fenner worked on myxamatosis with CSIRO’s Ian Clunies-Ross and Macfarlane-Burnett. Mid-last century, they famously injected themselves with the myxoma virus, brought in to control the country’s rabbit plague, to prove it wouldn’t infect humans.
The introduction of myxamotosis was a big step forward in controlling a pest that had devastated huge areas of farmland and was costing millions in lost production. We’re continuing our work here to improve the effectiveness of the next generation rabbit biocontrol agent, calicivirus.
September 12 – 13 is the Biosecurity and Bioinvasion workshop in Canberra. Our experts are discussing how maths is essential in protecting Australia from the threat of pests and diseases as part of the International Year of the Maths of Planet Earth.
As part of National Science Week, the Queensland Centre for Advanced Technologies – affectionately known as QCAT – is inviting members of the public to a special Open Day to celebrate 20 years of research in Pullenvale.
Showcasing the amazing science and technology developed at the centre, the day will include shows from CSIRO Education, as well as demonstrations, displays and discussions on technologies that are transforming Australia’s industries.
Meet Dr Rob from TV’s SCOPE science show, talk to our experts about the latest innovations in energy, mining and robotics, see the labs and discover what amazing work is going on in your neighbourhood.
QCAT’s Executive Manager, Dr Michael Brünig, says Australia’s best and brightest scientists are eager to share their knowledge and experience with the community.
“From developing the world’s biggest robot to the world’s most accurate underground longwall coal mining guidance system, research coming out of QCAT has been at the forefront of Australia’s innovation for the past two decades,” said Dr Brünig.
“We want everyone who visits the Open Day to help us celebrate this milestone by leaving with at least one ‘wow’ moment. Whether that happens by talking to our researchers, watching Dr Rob blow up a gummy bear or touring labs by remote control with our robot, there is sure to be a ‘scien-terrific’ experience for everyone.”
- Science shows for all the family at 11.30am, 12.30pm and 1.30pm
- Stealth robots and unmanned aerial vehicles
- 3D mapping and clever navigation systems
- Public lectures in the auditorium
- Defence Science and Technology Organisation (DSTO) hypersonic research
- Displays from Rio Tinto Alcan and Metso Process Technology and Innovation
- A chance to win one of seven Raspberry Pi® mini-computers that you can code at home.
For more information visit www.csiro.au/QCAT-OpenDay.
What: Queensland Centre for Advanced Technologies Open Day
When: 10am to 3pm, Saturday 17 August 2013
Where: 1 Technology Court, Pullenvale 4069 (located at on the corner of Moggill Road and Bainbridge Drive, Pullenvale)
Important information for visitors: QCAT is an industrial research facility and so for safety reasons, visitors are advised to wear closed footwear (i.e. no thongs, clogs or sandals).
About the Queensland Centre for Advanced Technologies
The Queensland Centre for Advanced Technologies (QCAT) is Australia’s largest integrated research and development precinct for the resources and associated advanced technology industries.
Officially opened in 1993, QCAT was established as a cooperative venture between CSIRO and the State of Queensland as a centre of excellence in mining research, iron ore and coal processing, energy research, autonomous systems and social science.
Along with CSIRO, QCAT also houses the Defence Science and Technology Organisation (DSTO) and commercial tenants Applied Mining Technologies Pty Ltd, BHP Billiton Carbon Steel Technical Marketing Group, CET Group, GeoTek Solutions, Metso and Rio Tinto Alcan Queensland Research and Development Centre.
QCAT has over 380 workers on site, making it one of the largest centres of employment in the region.
Meet the people who collaborated with artist Eleanor Gates-Stuart on StellrScope. You can click on the images to read their experiences of the science-art collaboration.
Eleanor is our science art fellow, and she created StellrScope for her Centenary of Canberra Science Art Commission.
You can see the 3d-interactive artworks she created in the StellrScope exhibition at Questacon this August.
You can also see her work this month at Hot Seeds at CSIRO Discovery.
These beautiful artworks were created by Eleanor Gates-Stuart, CSIRO Science Art Fellow. She created them for StellrScope, her Centenary of Canberra Science Art Commission.
In StellrScope Eleanor explores the story connecting the Canberra region to wheat, which is Australia’s major food crop. The region has been a focus of wheat research from the times of pioneer wheat breeder William Farrer to today’s research at CSIRO.
Eleanor’s art is on display at the StellrScope exhibition at Questacon this August. StellrScope features video, print and installation artworks, so you can interact with the works and experience layers of biological information about wheat.
You can see some of Eleanor’s other work at Hot Seeds at CSIRO Discovery, which is also open during August.
Part of the Biosecurity Series
By guest blogger Professor Peter Doherty
It’s no big secret that we’re citizens of an increasingly globalized planet where ideas, information, goods and services get around very fast. One of the downsides of this brave new world is that the same is true for pests and pathogens.
The security services, customs officers and quarantine regulations/officials protect Australia from such invasions as much as possible, although given the volume of trade and human movement, stopping bad things at the borders can only be part of any effective strategy.
There’s also a need for continual environmental monitoring to make sure that nothing dangerous slips through which could compromise Australia’s agricultural industries, wildlife and natural environments.
When it comes to biodefence against invading viruses, bacteria, insects, plants, marine parasites (on the hulls of ships) and so forth, we have layers of operation that function both at the Federal and State level.
This is, of course, where the wonderful high security CSIRO Australian Animal Health Laboratory (AAHL) comes into its own, providing the essential diagnostic tools and facilities for safe studies of deadly viruses in animals that are unique to the South-east Asian region.
Apart from its service to the veterinary world, AAHL has also pioneered studies of bat-borne viruses like Hendra and Nipah (active to the North-West of Australia) that can transmit to people from infected horses and pigs respectively. These are classic cases of the “One Health” view CSIRO takes that stresses the intimate interplay between animal disease and human disease. Apart from the Henipaviruses, AAHL also has the facilities that allow CSIRO researchers to study the avian influenza A viruses, that are a looming threat to both domestic poultry and people.
The new CSIRO Biosecurity Flagship pulls together research capability from across CSIRO together with a broad range of collaborating centres and groups. Sharing information is vital for such activities. Clearly, Australia cannot afford to have “silos” and artificial barriers that in any sense compromise our biological security. Of ongoing concern are the hi-path variants of the avian influenza H5N1 viruses that continue to circulate in wild and domestic birds (and occasionally infect and kill people) in the countries to the north-west of Australia. While we’ve avoided that particular threat so far, the situation requires constant monitoring.
I’ve said nothing about plant, insect and fish pathogens, but there are many diseases of key species, such as bees, trout and salmon that we have so far managed to keep at bay.
The new CSIRO Biosecurity Flagship is a great step in the right direction, and we need to continue doing all that we possibly can to ensure the long-term health and wellbeing of all the life forms that inhabit our extraordinary and unique country.
Join the Conversation: #bflaunch
About the Author
Peter Doherty trained initially as a veterinarian and shared the 1996 Nobel Prize for Physiology or Medicine for discoveries concerning our immune defence against viruses. He published the non-fiction book “Sentinel Chickens: What Birds Tell Us About our Health and our World” in 2012, and his new book “Pandemics: What Everyone Needs to Know” will be available in Australia from October.
Follow Peter on twitter: @ProfPCDoherty
Part of the Biosecurity Series
By Michelle Beltrame, Ken McColl and Tanja Strive
‘Shhh. Be vewy vewy quiet, we’re wesearching viruses’.
If Elmer Fudd is the arch-enemy of Bugs Bunny, then it’s safe to say that we’re not only the arch-enemy of the European rabbit, but the fish known as the ‘rabbit of the waterways’ – the European carp.
We’re arming ourselves with viruses with the aim of keeping these two invasive species in check and to help protect Australia’s economy and environment. This strategy is called biological control (‘biocontrol’ for short) – using disease to tackle invasive pests.
The battle of the rabbit
The European rabbit is a serious threat to agriculture and biodiversity in Australia. Myxoma virus, released in 1950 and Rabbit Calicivirus Disease (RCD), released in 1996, have proven the only effective means to significantly reduce rabbit numbers. The benefits to the agricultural industries of these two biocontrol viruses are estimated at $70 billion.
The European rabbit was brought to Australia onboard the First Fleet in 1788, but only became a major pest in 1859 when 24 wild rabbits were released by a wealthy Victorian grazier keen on the sport of hunting, and, …well… they bred like wild rabbits! Soon millions of rabbits were competing with Australia’s livestock for feed and were damaging the environment and threatening our native animals.
Our predecessor, CSIR, conducted initial trials of myxomatosis that ultimately resulted in the release of the virus in 1950. It was the world’s first successful biocontrol program of a mammalian pest, taming a scourge that had threatened Australian agriculture and environment.
The initial release of myxoma virus led to a dramatic reduction of Australia’s rabbit population – killing 99.8 per cent of rabbits that caught the infection in some areas. Because the virus is spread by mosquitoes, it had its greatest impact in the highest rainfall areas but didn’t work as well in arid zones where mosquitoes can’t survive.
By the late 1950s, resistance to the myxoma virus was starting to build up in Australia’s rabbits. The virus became less effective and rabbit numbers increased, but not to pre-1950 levels.
RDC was first discovered in China in 1984 and soon after in other countries in Asia, Europe and in Mexico. The viral disease affects only European rabbits, and its discovery offshore alerted scientists to a potential new biocontrol for wild rabbits in Australia.
The introduction of calicivirus in Australia in 1996 again reduced rabbit numbers drastically, but it had greater impact in the arid zones and least impact in the higher rainfall areas. A few years ago we discovered that Australian rabbits in the higher rainfall areas actually carry a native calicivirus that may provide some immunity to the disease. This benign form of the virus is very similar, so we suspect it’s acting as an imperfect natural vaccine against the more virulent strain.
Calicivirus and myxomatosis are still having an impact, but over the years their effectiveness has declined. As a result, we’re currently researching different caliciviruses in Australian wild rabbits, and their interactions with RCD to help determine potential future implementations for rabbit biocontrol.
Curbing our carp numbers
Carp is a pest associated with the poor health of our rivers and wetlands. The fish was first introduced to Australia more than 100 years ago and is now rampant in the Murray-Darling Basin.
We’re currently investigating a disease called cyprinid herpesvirus-3, also known as koi herpesvirus (or KHV), as a potential new biocontrol agent to help eradicate carp from Australia. The virus first appeared in Israel in 1998, and spread rapidly throughout much of the world, although not to Australia or New Zealand. It causes high death rates in common carp and in the ornamental variety of carp known as koi carp. No other species of fish, including goldfish, are known to be affected by it.
We’re conducting our research within the world’s most sophisticated high containment facility within the CSIRO-Australian Animal Health Laboratory (AAHL), where we’re undertaking rigorous tests to determine the virus’ suitability for controlling carp.
We’ve identified that CyHV-3 does kill Australian carp, and it kills them quickly, and current research has shown that the virus doesn’t affect native Australian or any other introduced species of fish.
Over the next few years we’ll continue to test the susceptibility of other fish species to CyHV-3 and address questions regarding the safety of possible widespread distribution of the virus, both for humans and for other animal species
Join the Conversation: #bflaunch
About the Authors
Dr Ken McColl, Research Scientist at CSIRO’s Australian Animal Health Laboratory, Geelong.
Ken is a veterinary virologist and pathologist specialising in the research and diagnosis of diseases of aquatic animals. For the past few years, Dr McColl’s major interest has centred on the possible use of koi herpesvirus (KHV) as a biological control agent for carp in Australia.
Dr Tanja Strive, Research Team Leader, CSIRO Ecosystem Sciences.
Tanja is a molecular virologist, and her current research focuses on various aspects of the biological control of vertebrate pest species, in particular rabbits. Key projects investigate: a) the interactions of different co-occurring rabbit pathogens in the field and the implications for rabbit control, b) the molecular virulence mechanisms of rabbit calicivirus, c) the selection of suitable virus strains for successive and ongoing field releases, and d) The evolution of rabbit caliciviruses as a model system for emerging diseases.
By Simon Barry
Effective biosecurity protects Australia’s environment and industries, but managing risk is an uncertain business. That’s why we need statistics.
Australia’s physical isolation has fostered the development of an amazing diversity of unique plants and animals, and has protected us from many serious pests and diseases that circulate around the world.
But we’re also a nation of traders — our prosperity is built on the import and export of goods and services.
With trade, however, can come exotic pests and diseases that have significant impacts on agriculture, the environment and economy.
In Australia’s history, a number of iconic examples are etched in the national psyche.
Rabbits were introduced into Australia several times, beginning with the First Fleet in 1788. Once established, they multiplied rapidly reaching plague proportions last century. They, in combination with introduced red fox and feral cat populations they support, are suspected of being the main cause of species loss in Australia.
The cactus prickly pear (Opuntia sp.) was introduced to Australia to start a cochineal dye industry. It spread quickly and at its height infested 24 million hectares of farmland with severe impacts on our agriculture.
While the community narrative is often framed around fear of invasion and potentially catastrophic consequences, the policy challenges are more complex and diffuse.
Decision makers need to assess risks of importation of different goods and materials against their possible benefits. They need to design surveillance systems to manage unacceptable risks; to certify that our exports are pest free; to predict their spread and impact when incursions of pests occur.
All of this is done against a backdrop of uncertainty.
Which species will successfully establish can be difficult to predict – impacts of exotic pests in agricultural systems may be predictable in some circumstances, but their environmental impacts are more uncertain. The linkage between biosecurity, trade and market access means that stakeholders may have a vested interest in the process. And the data required to predict accurately how successfully pest species establish here are limited or in most cases thankfully non-existent, so secondary sources, such as observations in other countries need to be used.
This is where statistics helps inform our decisions.
Statistics deals naturally with uncertainty and explicitly considers one of the most fundamental scientific questions: What can we logically infer about the world based on limited data?
It can support the development of established methodologies, such as assessing biological control agents, but it also opens up the possibility of using other existing and new data streams such as citizen-science collected data and genomics.
When these are combined with new algorithms and high performance computing, a range of exciting new opportunities arise that mean we’re better placed to tackle these issues than ever before.
For example, we are using these new computational informatics approaches to analyse whether or not red foxes have been eradicated in Tasmania.
Hard data is limited to a handful of fox carcasses discovered by members of the public, some footprints, a skull, DNA extracted from fox scats (poo) and blood found at the site of a chook pen raid from an unsighted predator.
As of 2010, the distribution of fox DNA-positive scats suggested a widespread fox population.
We’ve analysed the fox sighting data using a new statistical method known as approximate Bayesian computation, which uses computers to simulate millions of different plausible scenarios for the introduction and growth of the fox population.
Our analysis of the data up until 2013 provides different conclusions — that the introduced fox population is most likely extinct, or small and probably demographically weak.
Rather than worry us, the conflict between this result and the analysis based on scats is a healthy one and will drive research efforts to reconcile these differences.
We’re also using statistic to monitor the risk of pests and diseases which threaten Australia’s honeybee industry and many horticultural industries that rely on bees for pollination.
Australia is one of the only countries free of the mite Varroa destructor. Varroa has had a huge impact on global beekeeping as bee populations overseas have been decimated. Thankfully, it has yet to reach Australia and here is a need for early detection so that eradication could begin.
We are using shipping data from the Lloyds registry and interception data on exotic bees and bee pests from Australian quarantine officers to resolve the relative risk of different overseas locations and the reduction of this risk due to journey duration.
Effective biosecurity will continue to be important in maintaining the efficiency of Australian agricultural industries and to protect the environment.
These two examples demonstrate how mathematical and statistical sciences play a key role and Australia is well placed to innovate in this area.
Join the Conversation: #bflaunch
We’re hosting A Planet at Risk: Bioinvasion and Biosecurity workshop in Canberra in September. Visit the website for more details.
About the Author
Dr Simon Barry is Program Leader of Environmental Informatics, CSIRO Biosecurity Flagship.
Simon uses his expertise in modelling and monitoring methodologies to lead research projects with the aim of helping environmental resource managers and stakeholders understand what resources we have, their quality and how to manage them for sustainability.
By Carrie Bengston
What would happen if zombies invaded the planet? World War Z tells the story with Brad Pitt and a much bigger film budget than we have.
But it will hearten you to know that a team in Canada has actually crunched the numbers for a zombie apocalypse. They created a mathematical model for zombie infection, suggesting that only quick, aggressive attacks can stave off the doomsday scenario.
The take home message from the maths? Hit ‘em hard and hit ‘em often.
Maths can help us explore all kinds of real and hypothetical scenarios. You might not think it, but maths is vital in understanding the complex and dynamic planet we call home.
This was made clear last week at Mathematics of Planet Earth Year: The Conference, where over 200 people gathered to hear what maths is telling us about our precious planet.
For our young graduate fellows who are test driving a maths research career, the conference was a chance to see the limitless applications of their chosen field. These include an amazing variety of natural and human-organised aspects of planet Earth discussed during the conference.
From understanding climate and weather patterns to identifying pests that threaten our biosecurity using 3D insect imaging, it was evident how important maths is in understanding the many challenges facing Earth today.
Mathematical modelling has even been used to protect people in earthquake-prone areas, promote sustainable dairy farming and watch a virus spread within a plant.
Maths adds a lot of value to our own research too. For instance, our mathematical scientists have contributed to important discoveries about Alzheimer’s disease. Take a look:
2013 is the International year of Mathematics of Planet Earth. Learn more about how maths and stats are helping us understand the challenges of our world.
Part of the Biosecurity Series
By John Lowenthal and Andrew Bean
Zoonoses are diseases that have the ability to spread from animals to people, and they include some very well known diseases such as tuberculosis, flu and rabies, as well as some less familiar newcomers such as the Nipah and Melaka viruses.
In recent times zoonoses have accounted for more than 70 per cent of all emerging diseases, including H7N9 and H5N1 avian influenza, SARS, and MERS. What’s interesting is that a great deal of these zoonotic viruses that now pose a problem for humans appear to originate in either bats or poultry.
This highlights our need to understand not just what is happening in the human, but also what is happening in the animal. Wild animals such as bats and migratory water birds are the natural ‘reservoir’ hosts for many zoonotic infections and little is known about how they carry these viruses without showing signs of disease.
Other animals, including horses, pigs, chickens and even people are ‘spillover’ hosts, meaning they are highly susceptible to these viruses, and infection is usually deadly.
The recent growth and geographic expansion of human populations and the advance of agriculture into wildlife habitats has meant that now, more than ever, there is a greater risk of emerging infectious diseases being transmitted to people from wild and domesticated animals.
In addition, the impact of climate change has resulted in disturbances in eco-systems and a re-distribution of disease hosts and carriers. Increased global travel means a greater likelihood that new infectious agents will rapidly spread amongst the human population.
The World Health Organization has warned that the source of the next human pandemic is likely to be zoonotic, and that wildlife is a prime culprit. While the current list of known emerging infectious diseases is a major concern, it is the unknown virus lurking out there, with a potential for efficient human to human transmission that may pose the biggest pandemic threat.
A rapidly spreading lethal airborne zoonotic virus would, of course, be a major concern. You may remember the 2011 movie Contagion, which showed a fast-moving epidemic and the struggle to find a cure and control the panic. The ABC’s Catalyst story Virus Hunters also demonstrates the threat of quickly spreading diseases, and looks at the research our scientists do in the high containment facilities at the Australian Animal Health Laboratory.
If we want to fight these emerging threats and come out on top, we need to take a different approach to what we have done in the past and integrate medical, veterinary, ecological and environmental research.
This is what we refer to as the One Health approach – a combined approach to animal, human and environmental health, and the idea that we can all benefit from working together to value and solve the health problems of the world and reduce the risk of the next pandemic.
We believe it’s important to study and compare the disease in both the natural and spillover hosts. For example, understanding the differences between the immune systems of domesticated and wild animal hosts and comparing them to people is crucial for identifying the underlying disease mechanisms involved in zoonotic infections, and for developing new strategies for disrupting their transmission to humans.
This has important implications for predicting, preventing and controlling spillover events, and for the development of new therapeutics, vaccines and diagnostics.
Improving knowledge, prevention and treatment of zoonoses is the focus of the One Health research that we’re undertaking with our national and international partners, and within our unique high containment facility at AAHL– the world’s most sophisticated high containment facility. Focusing our research efforts in this area will assist in facilitating the development and application of effective and sustainable community health strategies. There is a growing view that a One Health approach will be critically important for our preparedness for the next zoonotic pandemic.
Join the Conversation: #bflaunch
About the Authors
John Lowenthal is Theme Leader for A One-Health approach to Emerging Infectious Diseases, CSIRO Biosecurity Flagship
John’s research is in the area of veterinary health and immunology, including studying the innate immune responses to viral diseases, assessing the ability of immune modulators such as cytokines to enhance resistance to disease and improve vaccine efficacy, using RNA interference to modulate disease-resistance, development of novel therapeutics for zoonotic viruses (H5N1 flu, Hendra virus) and the development of disease-resistant animals.
Andrew Bean is Stream Leader for Animal Biosecurity, CSIRO Biosecurity Flagship.
Andrew is an immunologist working to improve animal and human health with a ‘One Health’ approach. He joined CSIRO’s Australian Animal Health Laboratory in 1998 and the emphasis of his work is now on the innate immune response and the therapeutic and immuno-enhancing qualities of cytokines with the potential to improve health. His current research areas include avian influenza, Hendra virus, immune molecules and receptors, developing and assessing antiviral therapy, vaccines and adjuvants and therapeutics.
Part of the Biosecurity Series
By Gary Fitt, Director of CSIRO’s Biosecurity Flagship
When our biosecurity scientists introduce themselves to people outside the organisation and say their job is to help to protect Australia from nasty pests and diseases, they’re normally met with a puzzled expression. Soon the puzzlement turns to awe, and is followed by questions like ‘You mean you get to wear those big suits like Dustin Hoffman in the Hollywood thriller Outbreak?’
While some of our scientists work in high containment laboratories, kitted out in special protective ‘space suits’ to research deadly diseases, our work in biosecurity is much broader.
Biosecurity threats extend beyond infectious diseases to include weeds, invasive animals and insects. These all have the potential to devastate our crops, livestock and farming profits, our environment and even human health.
Historically, Australia’s strong quarantine measures and geographic isolation have protected us from some of the most serious impacts posed by exotic pests and diseases circulating around the world, but the movement of plants, animals and people across the globe and a changing climate are placing pressure on Australia’s future ability to protect itself from exotic pest and disease threats.
To address these challenges, we’ve reorganised our biosecurity related research activities into our new Biosecurity Flagship (you can find the full details in the brochure) to bring scale and connectivity to help Australia prepare for and prevent the spread and impacts of pests and diseases.
What’s a Flagship you ask? In a nut-shell it’s a large-scale research program which uses world-class science to deliver powerful solutions that tackle Australia’s major challenges and opportunities. This new flagship focuses our research across animal, plant and environmental science to more rapidly develop solutions to address Australia’s major biosecurity challenges.
Australians are aware of the damage that diseases, weeds, invasive animals and insects can inflict on crops, livestock, properties, farm profits and on human health. Biosecurity is all about preventing or keeping the impact of these threats and outbreaks to a minimum. Through research, we are working to reduce the risk of pests and diseases entering Australia, as well as improving the effectiveness of our mitigation and eradication responses.
We’ve traditionally tackled wildlife, animal and human diseases completely separately, but what we’re doing now through the Flagship’s integrated activities is taking a ‘One Health’ approach to understanding how these viruses spread between wild animals, livestock and people, and how to reduce the risks or be prepared for rapid response.
For instance, to deal with zoonotic diseases (those that can pass from animals to people), we’re adopting a more coordinated approach to understanding the multidimensional links between wild animals, livestock production, the environment and global public health.
CSIRO’s One Health approach has already been successful with the development of a horse vaccine against the deadly Hendra virus. Flying foxes carry the disease, although they are not affected by it, and the virus is lethal when transmitted to horses and from infected horses to humans. By working together, we realised that there wasn’t much we could do to reduce bat populations, and vaccinating people would be too expensive and too lengthy a process. We identified the horse vaccine as the most direct and effective strategy for the protection of both people and horses, breaking the chain of virus transmission from flying foxes to horses, and then to people, and protecting the horses themselves from a devastating infection that would otherwise most likely lead to their death.
The improved coordination of biosecurity research through the Flagship will enable us to better safeguard public health, the environment and the economy into the future. It will also greatly assist other countries as they too strive to deal with the pests and diseases that continue to spread globally and threaten general health.
Biosecurity is a system of shared responsibility across layers of government, which needs a statistically sound understanding of risk, pathways of entry, optimised surveillance and rapid diagnosis. Working with national and international research bodies, and the operational agencies responsible for delivering biosecurity, we will work across all these issues to jointly tackle biosecurity threats head on.
Next Thursday marks the official launch of the Biosecurity Flagship. To celebrate the launch, over the coming week we will feature a series of blog posts highlighting some of the Flagship’s activities.
We’ll also be featuring a special post from our guest blogger, author, Nobel Laureate and 1997 Australian of the Year, Peter Doherty.
Join the Conversation: #bflaunch
About the Author
Dr Gary Fitt is Director CSIRO’s Biosecurity Flagship, and is focused on protecting Australia from the biosecurity threats and risks posed by serious exotic and endemic pests and diseases.
By Dr Andrew Johnson
On February 11, 1861, Robert O’Hara Burke reached the Gulf of Carpentaria. He described in his diary the environment as “a considerable portion is rangy but it is well watered and richly grassed”.
More than 150 years after the ill-fated Burke and Wills expedition, many Australians consider north Australia to be a place of limitless potential. Throughout the 20th century, governments promoted development in the north. With a few notable exceptions, these have ended in failure.
More recently, state and federal governments of both political persuasions have had the foresight and courage to mandate scientific investigations to quantify the capacity of the north’s land and water assets, and to understand constraints to sustainable development presented by market opportunities, transport infrastructure and land tenure.
The passionate commentary demonstrates the diversity of views and the breadth of misunderstanding about the challenges of the tropics. Indeed, there are perhaps more urban myths about northern Australia than any other part of the nation. So let’s get some facts on the table.
Our scientists have identified the capacity to sustainably double or triple the north’s irrigation area using renewable groundwater resources. The potential is even greater if surface water is used. History has shown the challenges. Unlocking investment requires confidence about the scale of opportunities, and knowing the risks. A scarcity of detailed information about soil and water availability made it difficult to establish water storage options or agricultural productivity estimates or establish locations for irrigation. The cost of acquiring reliable soil, water and agricultural productivity estimates has often been an insurmountable barrier to private and public investors.
Underdeveloped transport infrastructure and long distances increase the cost of accessing inputs and selling outputs, as well as reducing the mass, quality and value of commodities.
Inconsistency in land and water regulations across jurisdictions and lack of clarity within them poses significant barriers to investment. Northern Australian tenure systems are complex. There are multiple, often overlapping tenure types for the same piece of land. Administrative arrangements vary across state boundaries. There are new and emergent tenures for water and carbon that are uncertain and are evolving.
Despite this, there are positive developments. In the Gulf country, the federal and Queensland governments, with our researchers, have demonstrated methods for rapidly and economically quantifying water flow and function, identifying water storage options, constructing soil maps of high precision and combining them to establish estimates of regional agricultural production potential. In the east Kimberley, the tireless efforts of government and the community are now driving profound positive change in the Ord. These examples provide a blue print for irrigated agriculture across the north.
The establishment of mosaic irrigation for the beef industry will enable increased productivity by overcoming seasonal feed shortages and intensifying production. This will allow producers to improve long-term viability. A year-round feed supply will also enable more efficient use of existing beef industry infrastructure.
Smarter transport logistics that deliver least-cost pathways for existing infrastructure – critical where rerouting is often required in response to flooding – is essential. A focus on logistics will prioritise investment in strategic infrastructure such as holding yards, rest stops, road configuration, the location of abattoirs and more efficient use of ports.
We also need to address property rights. Changes to land tenure regimes have the potential to transform indigenous communities from welfare dependency to economic participation as well as creating a more positive environment for investment. Changes to tenure arrangements are under way that aim to enable more diverse uses and clarify access and use rights. Future efforts must continue to focus on pastoral lands and in clarifying Indigenous interests in land and water.
Perhaps at no time since Federation has the nation’s interest in the north been so strong. A positive agenda will benefit all Australians, especially indigenous peoples. Whatever the actions taken, many will take time to implement; there are no easy fixes. They require patience, persistence, flexibility and a long-term commitment from all stakeholders.
In 2000, Stephen Hawking dubbed the 21st century the ‘century of complexity’. UK urban planning expert Prof Michael Batty agrees and argues that as our cities become more complex and interconnected we’ll need to find new ways of making sense of them.
Prof Batty, from University College London, is in Melbourne this week to take part in an international forum ‘Sustainability and the City’. He will be presenting some of the most important developments in urban systems complexity studies and previewing key topics in his upcoming book, The New Science of Cities.
“With the world urbanising faster than ever before, more of what we do will take place in cities,” says Prof Batty.
“As cities become more complex we urgently need new ways of thinking to make sense of how cities are merging and interconnecting globally.”
Organised by CSIRO, with support from the University of Melbourne and the City of Melbourne, the ‘Sustainability and the City’ symposium will examine the latest science developments in urban research and explore the challenges and opportunities of a sustainable urban future.
Those taking part in the conversation include CSIRO science leader Dr Greg Foliente, Prof Peter Newman of the Curtin University Sustainability Policy Institute and Prof Bob Stimson of the Australian Urban Research Infrastructure Network.
Prof Newman, who is widely respected for his impact in both academia and practice, will present new ideas based on the ‘theory of urban fabrics’, which underpins the science and practice of planning cities.
Melbourne residents have a rare opportunity to hear and interact with this international panel of urban sustainability experts at the public forum on 12 June, Melbourne Town Hall from 3-7 pm.
More information about the symposium
Chris Johnson – Communication Manager
CSIRO Climate Adaptation Flagship
Mobile: +61 437 226 011
This week we headed down to CeBIT, one of the world’s biggest IT trade shows. Here are some highlights from the titanic tech-fest:
With the recent spout of online hacks, cyber security was a hot topic of discussion. The experts gave us a friendly reminder to be careful what we share online.
DIY 3D printing
We got a glimpse of the latest range of DIY 3D printers – the ultimate birthday present for any tech lover.
Take a load off
Need to relax? There were plenty of super sturdy cardboard chairs to sit on, and you could even grab a free massage.
It’s getting cloudy
It was all about cloud computing this year, with Minister Stephen Conroy launching the National Cloud Computing Strategy. The popular slogan going around was ‘say no to software’.
Harping on about Harper
Digital campaign guru Harper Reed made a special appearance, giving a captivating talk on his role as Chief Technology Officer for President Obama in 2012.
With so many stylish tech-heads roaming around, it almost felt like we were at Sydney Fashion Week. The top trends in tech fashion this season included kilts, wet-suits, German beer maid outfits and kangaroo costumes.
Food, glorious food
What good would a trade show be without free food! But forget lollies in bowls, we were spoiled with a popcorn machine and frozen slushies.
Hugs with bots
And finally, robot love was definitely in the air. Everyone was lining up to give our newly named museum robot a cuddle – including our own members of parliament. The University of Western Sydney also bought along their cute bots, who busted some killer moves.
Head to our website for more information on our stand at CeBIT.