Whether it’s sourdough, seeded rye, gluten-free or plain old white, there’s nothing like tucking into a fresh slice of bread. And it’s little wonder this age-old staple tastes so good – experts have been perfecting the art of bread making for thousands of years.
If we had to name who’s involved in bread making, most of us would probably identify the baker, the farmer who grows the wheat and maybe even the miller who grinds the wheat into flour. But how many people would think of the humble statistician? Dr Emma Huang would – and she’s eager to prove their worth in the process.
Emma is a statistical geneticist working with our Computational Informatics and Food Futures teams. She spends her days searching through thousands of genes for the few that affect yield and disease resistance in wheat.
By understanding the complex genetics of cultivated plants like wheat, Emma is helping farmers select the best crop varieties needed to produce the perfect loaf of bread.
“The impact of statistics in bread making starts well before preheating the oven. Statisticians are crucial in implementing efficient experimental design to compare different varieties of wheat for desirable characteristics,” says Emma.
After completing a Bachelor of Science in Mathematics at Caltech and a Doctor of Philosophy in Biostatistics at the University of North Carolina, Emma left the States to join our team in Brisbane.
Here she is using her mathematical expertise to detect regions of the wheat plants genome – or its inheritable traits – that are directly related to enhanced crop performance. This allows breeders to selectively breed specific genes, reducing the amount of time it takes to improve our food supply.
Her goal is to eventually be able to model the entire process of bread making, incorporating the effects of environment and genetics all the way from growing plants in the field, to milling the flour and baking the bread.
When she’s not crunching numbers in the name of food, Emma does her own private research into the best cuisine the world has to offer, indulging at world class restaurants like Spain’s El Celler de Can Roca. But fitness freaks don’t fret, she works off the extra calories playing water polo and going for ocean swims.
“Sometimes I think I was destined to be a statistical geneticist. Both my mother and aunt are qualified statisticians, my siblings all studied mathematics at university, and even my fiancé is a statistician!”
Who better to investigate the impact of genetics on our everyday life?
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Bats are amazing creatures. They’ve been around for at least 65 million years, and in that time have become one of the most abundant and widespread mammals on earth.
Our Bat Pack, a team of researchers at the Australian Animal Health Laboratory (AAHL) in Geelong, conduct a wide range of research into bats and bat borne viruses, and their potential effects on the human population, as part of the effort to safeguard Australia from exotic and emerging pests and diseases.
Their paper, published today in the journal Science, provides an insight into the evolution of the bat’s flight, resistance to viruses, and relatively long life.
The Bat Pack, in collaboration with the Beijing Genome Institute, led a team that sequenced the genomes of two bat species – the Black Flying Fox, an Australian mega bat, and the David’s Myotis, a Chinese micro bat.
Once the genomes were sequenced, they compared them to the genomes of other mammals, including humans, to find where the similarities and differences lay.
Chris Cowled, post-doctoral fellow at AAHL says the research may eventually lead to strategies to treat, or even prevent disease in humans.
“A deeper understanding of these evolutionary adaptations in bats may lead to better treatments for human diseases, and may eventually enable us to predict or perhaps even prevent outbreaks of emerging bat viruses,” Dr Cowled said.
“Bats are a natural reservoir for several lethal viruses, such as Hendra, Ebola and SARS, but they often don’t succumb to disease from these viruses. They’re also the only mammal that can fly, and they live a long time compared to animals similar in size.”
Flying is a very energy intensive activity that also produces toxic by-products, and bats have developed some novel genes to deal with the toxins. Some of these genes, including P53, are implicated in the development of cancer or the detection and repair of damaged DNA.
“What we found intriguing was that some of these genes also have secondary roles in the immune system,” Dr Cowled said.
“We’re proposing that the evolution of flight led to a sort of spill over effect, influencing not only the immune system, but also things like ageing and cancer.”
The research was a global effort involving the Beijing Genome Institute in Shenzhen, China; Australia’s national science research agency, the CSIRO; the University of Copenhagen; Wuhan Institute of Virology at the Chinese Academy of Sciences; the Naval Medical Research Center and Henry M. Jackson Foundation in the USA; Uniformed Services University, USA; and the Graduate Medical School at the Duke-National University of Singapore.
Media Contact: John Smith, CSIRO Animal, Food and Health Sciences; 07 3214 2960; 0467 736 671; email@example.com